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M9490384.TXT
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1994-09-19
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Document 0384
DOCN M9490384
TI [Kaposi's sarcoma in patients with kidney transplantation]
DT 9411
AU Vlasic-Matas J; Rumboldt Z; Puizina-Ivic N; Luksic B; Milas I; Dubravcic
M; Forempoher G; Klinika za unutrasnje bolesti Medicinskog fakulteta u
Zagrebui i; Klinickog bolnickog centra u Splitu.
SO Lijec Vjesn. 1994 Mar-Apr;116(3-4):95-7. Unique Identifier : AIDSLINE
MED/94335518
AB An anti-HIV negative patient with cadaveric renal transplant developed
Kaposi's sarcoma of the skin and gingiva 10 months after
transplantation, taking triple immunosuppression (cyclosporine,
azathioprine and prednisone). After reduction of the cyclosporine dose
and complete cessation of azathioprine administration, the tumor
regressed without rejection of renal transplant. The patient was a
carrier of HLA A2 and DR5. When Kaposi's sarcoma was diagnosed serologic
tests revealed reactivation of cytomegalovirus (CMV) infection. All this
combined with considerable pharmacological immunosuppression, made the
patient prone to develop Kaposi's sarcoma, which can regress with
adequate reduction of immunosuppression.
DE Adult Case Report English Abstract Human Immunosuppression/*ADVERSE
EFFECTS Kidney Transplantation/*ADVERSE EFFECTS Male Mouth
Neoplasms/*ETIOLOGY Sarcoma, Kaposi's/*ETIOLOGY Skin
Neoplasms/*ETIOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).